Resident Evil Requiem, more so than the past few entries in the long-running series, seems at first to fall in line with this approach. After a few scene changes through an F.B.I. office, an impressive if uncanny rendering of a Brooklyn city street (complete with bodegas advertising “Food Stamp”) and a moldering hotel, Requiem settles on the stately and crenelated Rhodes Hill Chronic Care Center, an old sanitarium turned into a mad scientist’s testing ground. That scientist, Victor Gideon, played with mealy, gold-toothed verve, has drawn the game’s two playable characters, Grace Ashcroft and Leon S. Kennedy, here to complete the final stages of his dastardly plan, which involves using Grace’s special provenance to unlock more aggressive forms of bioengineering.